XBridge BEH Phenyl 色譜柱
? 高化學(xué)穩(wěn)定的Ⅱ 型苯基柱
? 對芳香化合物有獨(dú)特的選擇性
? 三鍵鍵合方式，有效提高苯基抗流失性，避免苯基流失本底峰（UV），兼容LC/MS
? 溫度上限：低pH時80℃，高pH時60℃
BEH顆粒能夠顯著改善色譜峰形的關(guān)鍵因素是其在合成工藝中 采用了亞乙基橋結(jié)構(gòu)。亞乙基橋連接相鄰的兩個硅醇基，這 不僅增加了顆粒強(qiáng)度，同時也減少了游離的硅醇基位點(diǎn)，從 而減少硅醇基與樣品間不利的相互作用力。傳統(tǒng)的方法(例如 大量的封端(excessive end capping))僅限于封端試劑的空間位阻 效應(yīng)及在活性位點(diǎn)上連接配體。這樣，殘余的游離硅醇基暴 露后就會導(dǎo)致峰展寬和峰拖尾。亞乙基橋可減少游離的硅醇 基數(shù)量，使分子空間排布最適于配體鍵合及封端。控制這一 過程可有助于XBridge色譜柱得到卓越的峰形。
色譜柱在低pH流動相中柱壽命差的主要原因是鍵合相在酸性條件下發(fā)生水解。XBridge填料采用沃特世先進(jìn)的鍵合技術(shù)與封端技術(shù)，可以在低pH條件下表現(xiàn)出良好的配體穩(wěn)定性與色譜重現(xiàn)性。
Advantages of CORTECS C18 2.7 μm and XBridge BEH Phenyl X P 2.5 μm Columns for the Analysis of a Comprehensive Panel of Pain Management Drugs for Forensic Toxicology
In forensic toxicology, drug screening panels often include such commonly used substances such as opiates, benzodiazepines and stimulants. These panels are often analyzed by LC-MS using traditional C18 column technologies. Key considerations include the ability to chromatographically resolve the various pairs of isobaric compounds included in these panels, while maintaining good peak shape for a variety of compounds. In addition, when using traditional HPLC systems, the ability to analyze samples as rapidly as possible without exceeding the pressure limitations of the system is very important. This application note highlights the capabilities of Waters’ new CORTECS C18 2.7 μm Columns and XBridge BEH Phenyl XP 2.5 μm Columns for this type of application. In the case of the CORTECS C18 Column, the high efficiency packing of solid core 2.7 μm particles yields excellent performance that equals or exceeds competitive columns at lower operating backpressures. If alternative selectivity is desired, the phenyl functionality of the BEH phenyl column enhances the retention of opiate compounds. This enhanced retention can potentially result in reducing ion suppression from urinary matrix components. Both columns achieve excellent baseline separation between isomers, and the entire panel of 35 compounds, including opioids, benzodiazepines, stimulants, and other drugs of abuse can be analyzed in under 4 minutes at backpressures compatible with any HPLC system
品名 | 編號 |
XBridge BEH Phenyl Column, 130?, 5 μm, 4.6 mm X 100 mm, 1/pkg | 186003351 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 4.6 mm X 30 mm, 1/pkg | 186003331 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 4.6 mm X 50 mm, 1/pkg | 186003332 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 4.6 mm X 75 mm, 1/pkg | 186003333 |
XBridge BEH Phenyl Column, 130?, 5 μm, 2.1 mm X 100 mm, 1/pkg | 186003339 |
XBridge BEH Phenyl Column, 130?, 5 μm, 2.1 mm X 50 mm, 1/pkg | 186003338 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 1 mm X 50 mm, 1/pkg | 186003317 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 4.6 mm X 150 mm, 1/pkg | 186003335 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 4.6 mm X 100 mm, 1/pkg | 186003334 |
XBridge BEH Phenyl Column, 130?, 5 μm, 2.1 mm X 30 mm, 1/pkg | 186003337 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 4.6 mm X 250 mm, 1/pkg | 186003965 |
XBridge BEH Phenyl Column, 130?, 5 μm, 2.1 mm X 150 mm, 1/pkg | 186003340 |
XBridge BEH Phenyl Column, 130?, 5 μm, 3 mm X 100 mm, 1/pkg | 186003344 |
XBridge BEH Phenyl Column, 130?, 5 μm, 3 mm X 50 mm, 1/pkg | 186003343 |
XBridge BEH Phenyl Column, 130?, 5 μm, 3 mm X 30 mm, 1/pkg | 186003342 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 2.1 mm X 30 mm, 1/pkg | 186003321 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 2.1 mm X 50 mm, 1/pkg | 186003322 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 3 mm X 150 mm, 1/pkg | 186003329 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 3 mm X 100 mm, 1/pkg | 186003328 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 3 mm X 50 mm, 1/pkg | 186003327 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 3 mm X 30 mm, 1/pkg | 186003326 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 2.1 mm X 150 mm, 1/pkg | 186003324 |
XBridge BEH Phenyl Column, 130?, 3.5 μm, 2.1 mm X 100 mm, 1/pkg | 186003323 |
XBridge BEH Phenyl Column, 130?, 5 μm, 3 mm X 150 mm, 1/pkg | 186003345 |
XBridge BEH Phenyl Column, 130?, 5 μm, 3 mm X 250 mm, 1/pkg | 186003346 |
XBridge BEH Phenyl Column, 130?, 5 μm, 4.6 mm X 75 mm, 1/pkg | 186003350 |
XBridge BEH Phenyl Column, 130?, 5 μm, 4.6 mm X 250 mm, 1/pkg | 186003353 |
XBridge BEH Phenyl Column, 130?, 5 μm, 4.6 mm X 150 mm, 1/pkg | 186003352 |
XBridge BEH Phenyl Intelligent Speed (IS) Column, 130?, 3.5 μm, 4.6 mm X 20 mm, 1/pkg | 186003330 |
XBridge BEH Phenyl Method Validation Kit, 130?, 2.5 μm, 4.6 mm X 150 mm, 3/pkg | 186006778 |
XBridge BEH Phenyl Method Validation Kit, 130?, 2.5 μm, 3 mm X 150 mm, 3/pkg | 186006777 |
XBridge BEH Phenyl Method Validation Kit, 130?, 2.5 μm, 2.1 mm X 150 mm, 3/pkg | 186006776 |
XBridge BEH Phenyl Intelligent Speed (IS) Column, 130?, 5 μm, 2.1 mm X 20 mm, 1/pkg | 186003336 |
XBridge BEH Phenyl Intelligent Speed (IS) Column, 130?, 3.5 μm, 2.1 mm X 20 mm, 1/pkg | 186003320 |
XBridge BEH Phenyl Method Validation Kit, 130?, 2.5 μm, 4.6 mm X 50 mm, 3/pkg | 186006219 |
XBridge BEH Phenyl Method Validation Kit, 130?, 2.5 μm, 3 mm X 100 mm, 3/pkg | 186006218 |
XBridge BEH Phenyl Method Validation Kit, 130?, 2.5 μm, 2.1 mm X 100 mm, 3/pkg | 186006216 |
XBridge BEH Phenyl Method Validation Kit, 130?, 2.5 μm, 2.1 mm X 50 mm, 3/pkg | 186006215 |
XBridge BEH Phenyl Method Validation Kit, 130?, 3.5 μm, 2.1 mm X 100 mm, 3/pkg | 186003799 |
XBridge BEH Phenyl Method Validation Kit, 130?, 3.5 μm, 4.6 mm X 150 mm, 3/pkg | 186003803 |
XBridge BEH Phenyl Intelligent Speed (IS) Column, 130?, 3.5 μm, 3 mm X 20 mm, 1/pkg | 186003325 |
XBridge BEH Phenyl Method Validation Kit, 130?, 3.5 μm, 4.6 mm X 100 mm, 3/pkg | 186003802 |
XBridge BEH Phenyl Method Validation Kit, 130?, 3.5 μm, 3 mm X 150 mm, 3/pkg | 186003801 |
XBridge BEH Phenyl Method Validation Kit, 130?, 3.5 μm, 3 mm X 100 mm, 3/pkg | 186003800 |
XBridge BEH Phenyl Intelligent Speed (IS) Column, 130?, 5 μm, 4.6 mm X 20 mm, 1/pkg | 186003347 |
XBridge BEH Phenyl Method Validation Kit, 130?, 5 μm, 4.6 mm X 100 mm, 3/pkg | 186003807 |
XBridge BEH Phenyl Column, 130?, 5 μm, 4.6 mm X 30 mm, 1/pkg | 186003348 |
XBridge BEH Phenyl Method Validation Kit, 130?, 5 μm, 3 mm X 100 mm, 3/pkg | 186003805 |
XBridge BEH Phenyl Method Validation Kit, 130?, 5 μm, 2.1 mm X 150 mm, 3/pkg | 186003804 |
XBridge BEH Phenyl Column, 130?, 5 μm, 4.6 mm X 50 mm, 1/pkg | 186003349 |
XBridge BEH Phenyl OBD Prep Column, 130?, 5 μm, 30 mm X 50 mm, 1/pkg | 186003277 |
XBridge BEH Phenyl OBD Prep Column, 130?, 5 μm, 30 mm X 75 mm, 1/pkg | 186003278 |
XBridge BEH Phenyl Prep Guard Cartridge, 130?, 5 μm, 19 mm X 10 mm, 1/pkg | 186003355 |
XBridge BEH Phenyl OBD Prep Column, 130?, 5 μm, 30 mm X 150 mm, 1/pkg | 186003276 |
XBridge BEH Phenyl Prep Guard Cartridge, 130?, 5 μm, 10 mm X 10 mm, 1/pkg | 186003354 |
XBridge BEH Phenyl XP Column, 130?, 2.5 μm, 2.1 mm X 150 mm, 3/pkg | 176002885 |
XBridge BEH Phenyl Prep Guard Cartridge, 130?, 5 μm, 30 mm X 10 mm, 1/pkg | 186006891 |
XBridge BEH Phenyl OBD Prep Column, 130?, 5 μm, 50 mm X 100 mm, 1/pkg | 186003940 |
XBridge BEH Phenyl XP Column, 130?, 2.5 μm, 2.1 mm X 30 mm, 1/pkg | 186006064 |
XBridge BEH Phenyl OBD Prep Column, 130?, 5 μm, 19 mm X 50 mm, 1/pkg | 186003356 |
XBridge BEH Phenyl OBD Prep Column, 130?, 5 μm, 19 mm X 100 mm, 1/pkg | 186003357 |
XBridge BEH Phenyl OBD Prep Column, 130?, 5 μm, 19 mm X 150 mm, 1/pkg | 186003358 |
XBridge BEH Phenyl OBD Prep Column, 130?, 5 μm, 30 mm X 100 mm, 1/pkg | 186003279 |
XBridge BEH Phenyl XP Column, 130?, 2.5 μm, 2.1 mm X 100 mm, 1/pkg | 186006067 |
XBridge BEH Phenyl XP Column, 130?, 2.5 μm, 2.1 mm X 150 mm, 1/pkg | 186006718 |
XBridge BEH Phenyl OBD Prep Column, 130?, 5 μm, 50 mm X 50 mm, 1/pkg | 186003936 |
XBridge BEH Phenyl OBD Prep Column, 130?, 5 μm, 19 mm X 250 mm, 1/pkg | 186004024 |
XBridge BEH Phenyl Method Validation Kit, XP Column, 130?, 2.5 μm, 3 mm X 50 mm, 3/pkg | 186006217 |
XBridge BEH Phenyl VanGuard Cartridge, 130?, 5 μm, 3.9 mm X 5 mm, 3/pkg | 186007798 |
XBridge BEH Phenyl XP Column, 130?, 2.5 μm, 2.1 mm X 100 mm, 3/pkg | 176002573 |
XBridge BEH Phenyl VanGuard Cartridge, 130?, 5 μm, 2.1 mm X 5 mm, 3/pkg | 186007796 |
XBridge BEH Phenyl VanGuard Cartridge, 130?, 3.5 μm, 3.9 mm X 5 mm, 3/pkg | 186007795 |
XBridge BEH Phenyl Method Validation Kit, 130?, 5 μm, 4.6 mm X 250 mm, 3/pkg | 186003809 |
XBridge BEH Phenyl VanGuard Cartridge, 130?, 3.5 μm, 2.1 mm X 5 mm, 3/pkg | 186007793 |
XBridge BEH Phenyl Method Validation Kit, 130?, 5 μm, 4.6 mm X 150 mm, 3/pkg | 186003808 |
相關(guān)產(chǎn)品
即問即答，我們在線為您服務(wù)！
